April 23, 2024

Drug storage considerations

Introduction: Hospitals are the final link in the use of drugs. Drugs go from the drug store to the patient through the pharmacy or are used clinically. Drug quality management must be maintained throughout to ensure drug quality. Safeguard human body drug safety. According to Article 18 of the "Regulations for the Implementation of the Quality Management Regulations for Pharmaceutical Business" of the State Food and Drug Administration, pharmaceutical wholesale and retail chain stores shall set up warehouses with different conditions of temperature and humidity according to the storage requirements of the drugs they handle.

Drug storage considerations

High temperatures in the storage environment, low boiling point liquids, and solid drugs that easily sublimate will volatilize, such as ethanol and camphor. After the elixir drug is volatilized by heat, the concentration of the drug changes, which affects the curative effect. Some medicines will accelerate their chemical changes due to high temperature and humidity, which will reduce the efficacy. For example, hydrogen peroxide solution will gradually decompose and fail under high temperature and excessive humidity conditions. It is mold that has a great influence on the storage of medicinal materials. Its suitable growth humidity is 80 to 90% RH, and when the relative humidity is less than 70%, mold growth is not easy. Humidity is too high, many solid drugs are prone to deliquescence, liquefaction, and the tablets disintegrate and absorb moisture into clumps, such as potassium iodide, gastric protein drunk and so on. In addition, drugs containing proteins, starch, gelatin, and sugars are susceptible to mildew and deterioration under excessive humidity. Some liquid medications in the case of high humidity, will absorb the moisture in the air and reduce its concentration, resulting in the use of agents are not allowed, such as anhydrous alcohol, acetic acid and so on. Some liquid preparations are susceptible to changes in quality under low temperature conditions.

Reduce points, such as 1% morphine hydrochloride and so on.

Hospitals are the final link in the use of drugs. Drugs go from the drug store to the patient through the pharmacy or to the clinic. Drug quality management must be implemented throughout to ensure the quality of drugs. Safeguard human body drug safety. According to Article 18 of the "Regulations for the Implementation of the Quality Management Regulations for Pharmaceutical Business" of the State Food and Drug Administration, pharmaceutical wholesale and retail chain stores shall set up warehouses with different conditions of temperature and humidity according to the storage requirements of the drugs they handle. In the wet season, in order to prevent drugs from losing moisture and moisture and lose their efficacy, an appropriate storage environment must be created. Practice has proved that using a constant temperature and humidity machine is an effective way to control and adjust the humidity in the library.

Therefore, the humidity must be strictly controlled in all aspects of the production and storage of drugs, so as to ensure the normal production and storage of drugs! The normal temperature in the drug storage condition refers to the temperature of 0 to 30°C; the cool place refers to the temperature of 0 to 20°C; the cold place refers to the temperature of 2 to 10°C, and the relative humidity of the three is 45% to 75% RH.

However, all medicines have a certain shelf life, which is often referred to as the validity period. The so-called validity period of drugs refers to the time limit for the drug to guarantee its quality and therapeutic effect under the prescribed storage conditions. Intuitively speaking, it is the time taken to reduce the active ingredient of the drug by 10% under the prescribed storage conditions.

If the drug storage conditions do not meet the specified requirements, such as high temperature and humidity, light and other factors, can accelerate the speed of drug degradation, that is, to shorten the effective period of the drug. Therefore, it is necessary to ensure that the quality of the drug is stable during the validity period. Whether it is a manufacturer, a wholesale company, a retail pharmacy, or a patient's home, or during the circulation and transportation of a drug, it must pay attention to the environmental conditions of the drug.

Constant temperature and humidity machine

1. Adopt world famous rotor and scroll compressors, high energy efficiency ratio, energy saving 20% ​​compared to traditional reciprocating compressors, more adequate cooling capacity, lower operating noise, more reliable, longer life; automatic Thermal expansion valve, dry filter. Valves and other refrigeration components can fully exert the compressor efficiency and effectively protect the compressor.

2. The fan is directly driven by the external rotor motor, which has the advantages of low noise, large air volume, high efficiency, compact structure, etc.; it can overcome problems such as slippage, looseness, and replacement of the belt.

3, high-performance electronic electrode humidifier: no bacteria, no pollution to the indoor air; no special requirements on water quality, no water treatment; independent humidifier control board, automatic water change cleaning, extended life, can automatically according to the humidification requirements Control the water level and humidification electrode current to achieve high-precision control, and truly meet the high-precision requirements;

4, improve the protection device to ensure safe operation of equipment: power supply phase, the wrong phase, the compressor over-current, high and low pressure, delay protection, fan overload, overheating electric heating, pressure-type wind protection device;

5, equipped with a sound operation and fault indicators, switches, operation at a glance;

6, imported microcomputer precision controller: LCD temperature and humidity display, user parameter settings, easy operation and precise control; high-precision temperature and humidity sensor, can automatically achieve temperature and humidity control; imported brand-name contactors, relays and other electrical components;

7, all stainless steel condensate tray and bottom water tray, electrostatic spraying sheet metal shell;

8, the unit is divided into water-cooled, split air-cooled and integrated air-cooled structure to meet the needs of different occasions.

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